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1

The canine model with chronic, complete atrio-ventricular block

Avram Oros, Jet D.M. Beekman, Marc A. Vos

Journal:

Pharmacology & Therapeutics

Year:

2008

Language:

english

File:

PDF, 1.50 MB

english, 2008

2

Beat-to-beat variations in activation recovery interval derived from the right ventricular electrogram can monitor arrhythmic risk under anesthetic and awake conditions in the canine chronic atrioventricular block model

Wijers, Sofieke C., Sprenkeler, David J., Bossu, Alexandre, Dunnink, Albert, Beekman, Jet D.M., Varkevisser, Rosanne, Aranda Hernández, Alfonso, Meine, Mathias, Vos, Marc A.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.57 MB

english, 2017

3

IKs contributes importantly to ventricular repolarization in conscious dogs

Jurren M. Van Opstal, Paul G. Volders, Milan Stengl, E. Martel, Uwe Gerlach, Roel L. Spätjens, Jet D. Beekman, Karin R. Sipido, Marc A. Vos

Journal:

Journal of the American College of Cardiology

Year:

2003

Language:

english

File:

PDF, 178 KB

english, 2003

4

Anesthesia and Arrhythmogenesis in the Chronic Atrioventricular Block Dog Model

Dunnink, Albert, Sharif, Shahnam, Oosterhoff, Peter, Winckels, Stephan, Montagne, Denise, Beekman, Jet, van der Nagel, Roel, van der Heyden, Marcel A G, Vos, Marc A

Journal:

Journal of Cardiovascular Pharmacology

Year:

2010

Language:

english

File:

PDF, 760 KB

english, 2010

5

Characterization of In Vitro and In Vivo Lesions Made by a Novel Multichannel Ablation Generator and a Circumlinear Decapolar Ablation Catheter

MAURITS C.E.F. WIJFFELS, MATTHIJS VAN OOSTERHOUT, LUCAS V.A. BOERSMA, RANDY WERNETH, CHRIS KUNIS, BETTY HU, JET D.M. BEEKMAN, MARC A. VOS

Journal:

Journal of Cardiovascular Electrophysiology

Year:

2009

Language:

english

File:

PDF, 265 KB

english, 2009

6

Atrial-specific drug AVE0118 is free of torsades de pointes in anesthetized dogs with chronic complete atrioventricular block

Oros, Avram, Volders, Paul G.A., Beekman, Jet D.M., van der Nagel, Theo, Vos, Marc A.

Journal:

Year:

2006

Language:

english

File:

PDF, 620 KB

english, 2006

7

Pro-Arrhythmic Ventricular Remodeling Is Associated With Increased Respiratory and Low-Frequency Oscillations of Monophasic Action Potential Duration in the Chronic Atrioventricular Block Dog Model

Sprenkeler, David Jaap, Beekman, Jet D. M., Bossu, Alexandre, Dunnink, Albert, Vos, Marc A.

Journal:

Frontiers in Physiology

Year:

2019

Language:

english

File:

PDF, 571 KB

english, 2019

8

General Information

Oros, Avram, Volders, Paul G.A., Beekman, Jet D.M., van der Nagel, Theo, Vos, Marc A.

Journal:

Journal of the American Medical Directors Association

Year:

2010

Language:

english

File:

PDF, 40 KB

english, 2010

9

P4-16

Oros, Avram, Volders, Paul G.A., Beekman, Jet D.M., Van der Nagel, Th., Goegelein, H., Vos, Marc A.

Journal:

Year:

2006

Language:

english

File:

PDF, 64 KB

english, 2006

10

High-Rate Pacing Reduces Variability of Repolarization and Prevents Repolarization-Dependent Arrhythmias in Dogs With Chronic AV Block

PETER OOSTERHOFF, MORTEN B. THOMSEN, JOEP N. MAAS, NICO J.M. ATTEVELD, JET D.M. BEEKMAN, HAROLD V.M. VAN RIJEN, MARCEL A.G. VAN DER HEYDEN, MARC A. VOS

Journal:

Journal of Cardiovascular Electrophysiology

Year:

2010

Language:

english

File:

PDF, 312 KB

english, 2010

11

Vernakalant is devoid of proarrhythmic effects in the cAVB dog

Varkevisser, Rosanne, Tieland, Ralph, Beekman, Jet, van der Heyden, Marcel, Vos, Marc

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2014

Language:

english

File:

PDF, 45 KB

english, 2014

12

Beat-to-beat variability of repolarization as a new biomarker for proarrhythmia in vivo

Varkevisser, Rosanne, Wijers, Sofieke C., van der Heyden, Marcel A.G., Beekman, Jet D.M., Meine, Mathias, Vos, Marc A.

Journal:

Year:

2012

Language:

english

File:

PDF, 983 KB

english, 2012

13

Differences in fatty acid composition between cerebral brain lobes in juvenile pigs after fish oil feeding

Dullemeijer, Carla, Zock, Peter L., Coronel, Ruben, Den Ruijter, Hester M., Katan, Martijn B., Brummer, Robert-Jan M., Kok, Frans J., Beekman, Jet, Brouwer, Ingeborg A.

Journal:

British Journal Of Nutrition

Year:

2008

Language:

english

File:

PDF, 91 KB

english, 2008

14

Calcium release near l-type calcium channels promotes beat-to-beat variability in ventricular myocytes from the chronic AV block dog

Antoons, Gudrun, Johnson, Daniel M., Dries, Eef, Santiago, Demetrio J., Ozdemir, Semir, Lenaerts, Ilse, Beekman, Jet D.M., Houtman, Marien J.C., Sipido, Karin R., Vos, Marc A.

Journal:

Journal of Molecular and Cellular Cardiology

Year:

2015

Language:

english

File:

PDF, 911 KB

english, 2015

15

The inward rectifier current inhibitor PA-6 terminates atrial fibrillation and does not cause ventricular arrhythmias in dedicated goat and dog models

Ji, Yuan, Varkevisser, Rosanne, Opacic, Dragan, Bossu, Alexandre, Kuiper, Marion, Beekman, Jet D M, Yang, Sihyung, Khan, Azinwi Phina, Dobrev, Dobromir, Voigt, Niels, Wang, Michael Zhuo, Verheule, San

Journal:

British Journal of Pharmacology

Year:

2017

Language:

english

File:

PDF, 1.34 MB

english, 2017

16

Vernakalant is devoid of proarrhythmic effects in the complete AV block dog model

Varkevisser, Rosanne, van der Heyden, Marcel A.G., Tieland, Ralph G., Beekman, Jet D.M., Vos, Marc A.

Journal:

European Journal of Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.73 MB

english, 2013

17

Discrepancy Between Acute and Long-Term Effects of the Calmodulin-Camkii-Calcineurin Pathway on Arrhythmogenesis in the CAVB Dog

Bourgonje, Vincent J.A., Schoenmakers, Marieke, Beekman, Jet D.M., van der Nagel, Roel, de Windt, Leon J., van Veen, Toon A.B., Vos, Marc A.

Journal:

Year:

2009

Language:

english

File:

PDF, 104 KB

english, 2009

18

AB40-3

Thomsen, Morten B., Oros, Avram, Schoenmakers, Marieke, Van Opstal, Jurren M., Beekman, Jet D.M., Vos, Marc A.

Journal:

Year:

2006

Language:

english

File:

PDF, 71 KB

english, 2006

19

Downregulation of ion channel subunits underlying electrical remodeling in the dog with complete atrio-ventricular block: Regional and temporal considerations

Ramakers, Christian, Volders, Paul G.A., Donker, Dirk W., Beekman, Jet, Moorman, Antoon F.M., Vos, Marc A.

Journal:

Year:

2005

Language:

english

File:

PDF, 97 KB

english, 2005

20

P4-20

Thomsen, Morten B., Beekman, Jet D.M., Attevelt, Nico, Chiba, Katsuyoshi, Vos, Marc A.

Journal:

Year:

2006

Language:

english

File:

PDF, 65 KB

english, 2006

21

Electrophysiological measurements that can explain and guide temporary accelerated pacing to avert (re)occurrence of torsade de pointes arrhythmias in the canine chronic atrioventricular block model

Wijers, Sofieke C., Bossu, Alexandre, Dunnink, Albert, Beekman, Jet D.M., Varkevisser, Rosanne, Aranda Hernández, Alfonso, Meine, Mathias, Vos, Marc A.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.20 MB

english, 2017

22

An Augmented Negative Force-Frequency Relationship and Slowed Mechanical Restitution Are Associated With Increased Susceptibility to Drug-Induced Torsade de Pointes Arrhythmias in the Chronic Atrioventricular Block Dog

Sprenkeler, David J., Bossu, Alexandre, Beekman, Jet D. M., Schoenmakers, Marieke, Vos, Marc A.

Journal:

Frontiers in Physiology

Year:

2018

Language:

english

File:

PDF, 2.53 MB

english, 2018

23

Electrophysiological and proarrhythmic parameters in transmural canine left-ventricular needle biopsies

S. Cora Verduyn, Jérôme G. M. Jungschleger, Milan Stengl, Roel L. H. M. G. Spätjens, Jet D. M. Beekman, Marc A. Vos

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2004

Language:

english

File:

PDF, 423 KB

english, 2004

24

Beat-to-Beat Variability of Repolarization Determines Proarrhythmic Outcome in Dogs Susceptible to Drug-Induced Torsades de Pointes

Morten B. Thomsen, Paul G.A. Volders, Jet D.M. Beekman, Jørgen Matz, Marc A. Vos

Journal:

Journal of the American College of Cardiology

Year:

2006

Language:

english

File:

PDF, 798 KB

english, 2006

25

Beat-to-Beat Variability in Preload Unmasks Latent Risk of Torsade de Pointes in Anesthetized Chronic Atrioventricular Block Dogs

Stams, Thom RG, Oosterhoff, Peter, Heijdel, Atty, Dunnink, Albert, Beekman, Jet DM, van der Nagel, Roel, van Rijen, Harold VM, van der Heyden, Marcel AG, Vos, Marc A

Journal:

Circulation Journal

Year:

2016

Language:

english

File:

PDF, 2.15 MB

english, 2016

26

Pro-Arrhythmic Ventricular Remodeling Is Associated With Increased Respiratory and Low-Frequency Oscillations of Monophasic Action Potential Duration in the Chronic Atrioventricular Block Dog Model

Sprenkeler, David Jaap, Beekman, Jet D. M., Bossu, Alexandre, Dunnink, Albert, Vos, Marc A.

Journal:

Frontiers in Physiology

Year:

2019

File:

PDF, 571 KB

2019

27

High-Septal Pacing Reduces Ventricular Electrical Remodeling and Proarrhythmia in Chronic Atrioventricular Block Dogs

Stephan K.G. Winckels, Morten B. Thomsen, Peter Oosterhoff, Avram Oros, Jet D.M. Beekman, Nico J.M. Attevelt, Leo Kretzers, Marc A. Vos

Journal:

Journal of the American College of Cardiology

Year:

2007

Language:

english

File:

PDF, 695 KB

english, 2007

28

Late Na+ Current Inhibition by Ranolazine Reduces Torsades de Pointes in the Chronic Atrioventricular Block Dog Model

Gudrun Antoons, Avram Oros, Jet D.M. Beekman, Markus A. Engelen, Marien J.C. Houtman, Luiz Belardinelli, Milan Stengl, Marc A. Vos

Journal:

Journal of the American College of Cardiology

Year:

2010

Language:

english

File:

PDF, 1.08 MB

english, 2010

29

Beat-to-beat variability of repolarization determines proarrhythmic outcome in dogs susceptible to drug-induced torsades de pointes

Thomsen, Morten B., Matz, Jørgen, Beekman, Jet D., Volders, Paul G.A., Vos, Marc A.

Journal:

Year:

2005

Language:

english

File:

PDF, 81 KB

english, 2005

30

Decreasing the infusion rate reduces the proarrhythmic risk of NS-7: confirming the relevance of short-term variability of repolarisation in predicting drug-induced torsades de pointes

Elke Detre, Morten B Thomsen, Jet D Beekman, Karl-Uwe Petersen, Marc A Vos

Journal:

British Journal of Pharmacology

Year:

2005

Language:

english

File:

PDF, 231 KB

english, 2005

31

Effects of K201 on repolarization and arrhythmogenesis in anesthetized chronic atrioventricular block dogs susceptible to dofetilide-induced torsade de pointes

Thom R.G. Stams, Avram Oros, Roel van der Nagel, Jet D.M. Beekman, Paul Chamberlin, Howard C. Dittrich, Marc A. Vos

Journal:

European Journal of Pharmacology

Year:

2011

Language:

english

File:

PDF, 983 KB

english, 2011

32

EFFECTS OF K201 ON REPOLARIZATION AND ARRHYTHMOGENESIS IN DOGS WITH CHRONIC COMPLETE ATRIOVENTRICULAR BLOCK

Thom R. Stams, Avram Oros, Roel van der Nagel, Jet D. Beekman, Paul Chamberlin, Howard C. Dittrich, Marc A. Vos

Journal:

Journal of the American College of Cardiology

Year:

2011

Language:

english

File:

PDF, 192 KB

english, 2011

33

Torsade de pointes arrhythmias arise at the site of maximal heterogeneity of repolarization in the chronic complete atrioventricular block dog

Dunnink, Albert, Stams, Thom R.G., Bossu, Alexandre, Meijborg, Veronique M.F., Beekman, Jet D.M., Wijers, Sofieke C., De Bakker, Jacques M.T., Vos, Marc A.

Journal:

Year:

2016

Language:

english

File:

PDF, 634 KB

english, 2016

34

Relevance of calmodulin/CaMKII activation for arrhythmogenesis in the AV block dog

Schoenmakers, Marieke, Bourgonje, Vincent J.A., Beekman, Jet D.M., van der Nagel, Roel, Houtman, Marien J.C., Miedema, Lars F., Antoons, Gudrun, Sipido, Karin, de Windt, Leon J., van Veen, Toon A.B.

Journal:

Year:

2012

Language:

english

File:

PDF, 2.28 MB

english, 2012

35

The electromechanical window: Not superior to QT as a surrogate parameter for risk of dofetilide-induced Torsade de Pointes in the anesthetized canine complete atrioventricular block model

Stams, Thom, Bourgonje, Vincent, Beekman, Jet, Schoenmakers, Marieke, van der Nagel, Roel, Oosterhoff, Peter, van Opstal, Jurren, Vos, Marc

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2014

Language:

english

File:

PDF, 61 KB

english, 2014

36

AV-Block and Conduction Slowing Prevail Over TdP Arrhythmias in the Methoxamine-Sensitized Pro-Arrhythmic Rabbit Model

VARKEVISSER, ROSANNE, VOS, MARC A., BEEKMAN, JET D., TIELAND, RALPH G., VAN DER HEYDEN, MARCEL A.

Journal:

Journal of Cardiovascular Electrophysiology

Year:

2015

Language:

english

File:

PDF, 728 KB

english, 2015

37

The Effect of an Entrainment Protocol on Ouabain-Induced Ventricular Tachycardia

MARC A. VOS, ANTON P.M. GORGELS, JET D.M. LEUNISSEN-BEEKMAN, PEDRO BRUGADA, HEIN J.J. WELLENS

Journal:

Pacing and Clinical Electrophysiology

Year:

1989

Language:

english

File:

PDF, 3.90 MB

english, 1989

38

Short-Lasting Episodes of Torsade de Pointes in the Chronic Atrioventricular Block Dog Model Have a Focal Mechanism, While Longer-Lasting Episodes Are Maintained by Re-Entry

Vandersickel, Nele, Bossu, Alexandre, De Neve, Jan, Dunnink, Albert, Meijborg, Veronique M.F., van der Heyden, Marcel A.G., Beekman, Jet D.M., De Bakker, Jacques M.T., Vos, Marc A., Panfilov, Alexande

Journal:

JACC: Clinical Electrophysiology

Year:

2017

Language:

english

File:

PDF, 1.38 MB

english, 2017

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